x6r

Sorry for the noob question, but is there any reason that the FrSky X4RSB (using S-bus) can't be used on a larger quad (S500 frame)? I plan on using it with an X7 and Holybro Pixhawk 2.4.6, and it seems to have all the functions of its larger X6R sibling, less the size, weight and (for me)...